Azizi Trainee Program Dyslipidemia A Case based Discussion

Presentation of Case:

• A 31-year-old married woman with hypercholesterolemia
• She is planning for pregnancy (history of two abortions).
• Skin lesions from the age of 5 years diagnosed as tuberous xanthoma at the age of 12.
• Diagnosis of hypercholesterolemia at the age of 12

Medications:

• Atorvastatin 40 mg bid + Colestyramine 4 g daily for 8 years
• Rosuvastatin 40 mg daily + Ezetimibe 10 mg daily for 2 years
• Rosuvastatin 40 mg bid ± Ezetimibe 10 mg daily for 8 years
• Serum cholesterol levels did not change significantly!
• She tells about taking Evolocumab injections for 2 months in two years ago resulting in reduction of serum cholesterol and LDL-C concentrations.